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Forum Description: Discuss prescription drugs and their effects
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Old 05-22-2008, 06:24 AM   #1
JahRed24
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What do u guys think about the whole potentiating benzos (xanax in my case) with White Grapefruit Juice and/or Tagament, which both are supposed to inhibit some enzyme or w/e and therefor increases the 'high'

I got this from Wikipedia:
"Eating grapefruits or drinking grapefruit juice while using alprazolam increases blood concentrations by inhibiting the intestinal metabolism.[38]

In fact, any drug that inhibits CYP3A4, for which alprazolam is a substrate, will increase serum concentrations of alprazolam significantly if administered prior or concurrently. Tagamet (cimetidine) is a widely used H2 blocker antacid that inhibits numerous cytochrome P450 enzymes.

Oral contraceptive pills reduce the clearance of alprazolam, which may lead to increased plasma levels of alprazolam and accumulation."

I've tried both these methods (the WHITE grapfruit juice and the Tagamet (cimetidine) of potentiatiing my xanax... I never really noticed much from drinking the white grapefruit juice (plus it taste isn't very nice either) but the Tagamet seemed to always work, but who knows? some of u guys should try both these methods with ur next Benzo adventure and let us know what ur results were....

It must be the WHITE GRAPEFRUIT JUICE and drink a full glass (8-12oz) about 35mins b4 u pop ur xanax..

If your using the Tagamet then take 200-400mgs, i reccommend taking 2 tagamet pills (each pill is 200mgs) about 45mins b4 u pop the xanax.

Lets me know whats ur guy's results are, Experiement my friends...

PS - I think the Tagamet works the best for potentiating my xanax a lot more then the White Grapefruit juice ever has. and i've done experiements many of times with taking xanax alone, with grapfruit juice and with the Tagamet. Plus its a lot easier to pop 2 pills then drinking a lot of that nasty white grapefruit juice ....so let us know what you guys think about these methods for enhancing benzos....btw Tagamet and White Grapefruit Juice work the same way when potentiating opiates!
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Old 05-22-2008, 07:23 AM   #2
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I heard that white grapefruit juice was the best GFJ, but does red ruby grapefruit juice work??

and is tagamet over the counter?
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Old 05-22-2008, 10:08 AM   #3
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Alcohol is the best benzo potenator. Of course, you might die.
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Old 05-22-2008, 07:58 PM   #4
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Quote:
Originally Posted by kil0
I heard that white grapefruit juice was the best GFJ, but does red ruby grapefruit juice work??

and is tagamet over the counter?
Yes Tagamet is over-the-counter here in the United States. And if you are gonna use GFJ then use the White Grapefruit Juice cuz its works better, a lot better ((i could get technically but u wouldnt understand anyways)). The red ruby gfj dont really work at all..
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Old 05-23-2008, 01:32 AM   #5
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damn that sucks, I cant find white GFJ anywhere! where'd you get it?
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Old 05-23-2008, 03:28 AM   #6
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opiates too i hear.
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Old 05-23-2008, 04:04 AM   #7
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yeah I want to try it with opiates because its supposed to work similarly, I got bored of benzos already.
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Old 05-23-2008, 04:26 AM   #8
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people have said the nod is incredible. just be careful mixing two downers.
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Old 05-23-2008, 05:15 AM   #9
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what two downers?
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Old 05-23-2008, 08:02 AM   #10
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oh well yeah of course opiates and benzos (xanax especially) potentiate eachother A LOT and lets u 'nod' out a lot easier/faster and with less amount of the opiate ur using...but im not talking about potentiating Benzos with other drugs like opiates/alcohol/weed/ect. im talkin about what i said it my original post about potentiating xanax with Tagamet and/or White Grapfruit Juice...


PS - poster asking about where to get White Grapefruit Juice? Usually in the "juices" isle at ur local super-market. - And now to answer ur question about where to get a bottle of 100% White Grapefruit Juice, well it can be purchased at ur local grocery store (around here its would be a Publix or Kroger) but whatever major grocery stores are around you then you can go there and find it there my friend. Just look down the "Juices" isle and its usually near by the other GFJ products like that "Ruby Red Grapefruit Juice" (Which doesnt work, so stick with White). GOod luck let us know how it goes. But remember in my personal opinion i would say 400mgs (max) potentiates the xanax (and other benzos) A LOT more then the White grapefruit juice...plus its easier to pop two lil tagamet pills then drinking like 20oz's of some nasty (to me at least ha) ass White Grapefruit Juice.
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