A Quick Acid Question

[Peace]

I would like to do LSD, but I have one question. Is it true that it can kill some of your chromosomes? Would this result in birth defects if the chromosomes were killed? Thanks in advance.

[stilanas]

I would like to do LSD, but I have one question. Is it true that it can kill some of your chromosomes? Would this result in birth defects if the chromosomes were killed? Thanks in advance.
Thanks DARE!

Here's erowid's take on it.

http://www.erowid.org/chemicals/lsd/lsd_writings3.shtml

LSD and Chromosomes
^^^^^^^^^^^^^^^^^^^^
an excerpt from The Natural Mind
by Andrew Weil

pp. 44-46:

Retrospective studies are risky ways of framing hypotheses; they are fraught
with logical traps known to the ancients, and it is remarkable that men of
science still fall for them.

The saga of LSD and chromosomes is a case in point, for much of the evidence
was of this retrospective sort. The initial hypothesis, first reported in
1967, was based on the observation that LSD users seemed to have a higher
frequency of broken chromosomes in certain white blood cells (lymphocytes)
than "normal" persons (1). The _New England Journal of Medicine_ gave this
observation great prominence in an editorial titled, "Radiomimetic Effects
of LSD," suggesting that the drug mimicked radiation in its damaging effects
on genetic material. Evidence that was more circumstantial then appeared:
LSD was shown to affect chromosomes of cells growing in test tubes; a few
mothers who had used LSD gave birth to deformed babies. The scientific and
lay press gave all these findings front-page attention. The National
Institute of Mental Health eagerly seized upon and disseminated the new
information in a propaganda campaign against LSD. And, for a few months,
use of the drug appeared to decline.

But throughout this campaign, a number of facts were overlooked. First was
the total absence of any prospective studies supporting the hypothesis. No
one had tested the hypothesis in a legitimate way -- by looking at
chromosomes before exposure to the drug, giving the drug in a controlled
fashion, and then keeping watch on chromosomes. Second was the known fact
that many things affect chromosomal integrity, among them such common drugs
as aspirin and chlorpromazine (Thorazine) and recent viral infections. No
effort was made to control for these other factors in the clinical cases.
Third was the general problem of tissue-culture studies: cells growing in
test tubes do not behave the way cells do in the body. In addition, the
doses of LSD that caused visible changes in chromosomes of tissue-culture
cells were far higher than the doses living cells get when a person takes
an acid trip. Fourth, chromosomal breaks are seen in cells of all people;
the arguments turned on a statistical difference in frequency, not an
all-or-nothing difference, and the frequency of chromosomal breaks in
lymphocytes seems to correlate more directly with laboratory technique than
with other variables. (The technique of preparing lymphocytes to make
chromosomes visible is complicated and likely to produce factitious
changes.) Fifth, the lymphocyte is one of the only cells in which human
chromosomes can ever be seen under the microscope. Even if the changes were
real, they said nothing about the state of chromosomes in other cells (such
as reproductive cells). In fact, through the whole controversy no one
showed _why_ it was bad to have broken chromosomes in your lymphocytes. It
sounds bad, certainly, but one cannot say that it is bad without making a
number of shaky assumptions.

All of these logical flaws in the medical arguments against LSD were obvious
in 1967. They do not mean that the hypothesis should never have been
published, but surely it should not have been promoted by the medical
profession, the press, and the National Institute of Mental Health without
more thought. And it is significant that these logical flaws were first
pointed out in the _Berkeley Barb_ and other underground newspapers at least
eight months before the _New England Journal of Medicine_ voiced similar
doubts. The necessary prospective studies were not published until the end
of 1969 (2). Not surprisingly, they failed to demonstrate any relationship
between LSD use and chromosomal changes. They generated very little
national publicity.

This episode ought to be profoundly embarassing to journal editors and
government scientists. At one stroke it created an irreparable gap between
users of drugs and drug experts. Since 1968 I have not met a single user of
hallucinogens who will believe any reports of medical damage associated with
drugs, and the use of hallucinogens has never been higher.

(1) M. M. Cohen, K. Hirshhorn, W. A. Frosch, "In Vivo and in Vitro
Chromosomal Damage Induced by LSD-25," _New England Journal of Medicine_ 227
(1967), p. 1043.

(2) J. H. Tjio, W. N. Pahnke, A. A. Kurland, "LSD and Chromosomes: A
Controlled Experiment," _Journal of the American Medical Association_ 210
(1969), p. 849. For a recent review of the whole field, see N. I.
Dishotsky, W. D. Loughman, R. E. Mogar, W. R. Lipscomb, "LSD and Genetic
Damage," _Science_ 172 (30 April 1971), p. 431.

[Fractual_]

nah dude, acid is one of the safest drugs out there... as long as you arent schitzophroenic or depressed or anything.

[TARABELLE]

Nobody I ever knew that took acid, which was quite a few, ever had babies with problems. I never had children of my own, so I can't speak from my own experience, sorry.

[Peace]

Cool, I just want to eat some acid! Thanks for the help.

[thechronic89]

acid is tight but i like doin shrooms now. its such a better trip and more natural

[Peace]

Shrooms are good; morning glory can be good if you can get a good trip.

[fuzzi green sweater]

hey im new at all this shit so bear wit me...alrite im thinkin of takin acid wit a friend of mine...i herd of a couple ways u can take it..like i herd u can put it in ur eye or mouth n shit...i dont really know much about it cept the hole trippin part...well if u can write back any good info on the best way to take it and shit that wud b cool....thanks

[eat_some_LSD]

The best way to take LSD is to just eat it. You really don't want to take a hit in the eye; it hits you extremely quickly, but everytime I've seen someone do it they started rolling around on the ground from the pain. ;)

[Chris_mate]

I have been considering taking some acid for a while now. So a friend of mine and I have decided that the time has come and our first (I hope of many) acid trip will be at a rave party this weekend. I have read all sorts of articles and experiences and a good part of them came from www.erowid.com (http://www.erowid.com/) any how wish us luck were gonna need it

[PurpleGel]

yeah, chris, you definitely will need that luck - a rave party is the last place i'd want to be dropping acid. perhaps consider the beach, forest, or mountains instead.

[fuzzi green sweater]

how much does it usually go for..im from jerzey so. i herd it wasnt that much,...later

[eat_some_LSD]

LSD, nowadays...is usually $15-20 a hit; though, if you find not-so-shadey connections, you should be be able to score doses for about $5-7 a piece.

A Rave is DEFINITELY not a good place to trip on LSD, especially for the first time. I'd recommend just rolling on some E, as LSD will leave you in an extremely vulnerable position. ;)

[stilanas]

hey im new at all this shit so bear wit me...alrite im thinkin of takin acid wit a friend of mine...i herd of a couple ways u can take it..like i herd u can put it in ur eye or mouth n shit...i dont really know much about it cept the hole trippin part...well if u can write back any good info on the best way to take it and shit that wud b cool....thanks
Just eat it. It's the easiest way to do it and you don't have to worry about a spill or leaving some unabsorbed.

[Ocean Byrd]

Ya, don't drop acid for the first time in a place that will be crowded; it can lead to very uncomfortable experiences.

[cshroom]

dont trip L iat a rave dude people can twist your head so bad so quik. you need someone you can trust ,love, nature, sunshine, starry night. trust me, a rave trip really isn't what you're lookin' for in SID

-peace IN love Real!

[Diamond Gord]

yeah, chris, you definitely will need that luck - a rave party is the last place i'd want to be dropping acid. perhaps consider the beach, forest, or mountains instead.I agree that for your first trip a rave probably isn't the best setting, in saying that I spend a lot of my tripping time in a nightclub on the dancefloor and when you think that you are experienced enough to try it, it is highly recommended.

[PurpleGel]

I agree that for your first trip a rave probably isn't the best setting, in saying that I spend a lot of my tripping time in a nightclub on the dancefloor and when you think that you are experienced enough to try it, it is highly recommended.
i guess the nightclubs just aren't my scene. i prefer tropical beaches and mountainous forests. but, if you're totally down, mind and soul, with the nightclub and the rave parties then i encourage you and others like you to trip acid there.

[Diamond Gord]

i guess the nightclubs just aren't my scene. i prefer tropical beaches and mountainous forests. but, if you're totally down, mind and soul, with the nightclub and the rave parties then i encourage you and others like you to trip acid there.Mountainous forests i could probably find but tropical beaches are in short supply in Scotland. The poor and umpredictable weather also means that outdoor tripping is not always possible.

[JamminOTR]

Oh man! Trippin in Scottland...that's like a dream for me...that could be beautiful. Go for a walk down some myseterious road and find a forest. L in Scottland...mmm!:)

[cauan]

That's all really new and very interesting to me cuz in Brazil people usually take it in Rave parties without complaints...but my firs time happened in a waterfall..it didn't hit...I'm the one who shared the acid and felt nothing...I'm about to try 1 or 2 the next time so it can really drive me to the psychedelic world.
Have a good trip tho Chris.

[flowerchildloves]

Luck Man>....im Tripp(n Harrrrd Coreee Right Now