PDA

View Full Version : Ultram?


natebozung535
12-02-2007, 07:19 PM
I just came across these, was wondering how they work? I think they are some sort of synthetic opiate but not sure at all, I don't have numbers/picture, but the guy said they are the generic ones.

JahRed24
12-03-2007, 04:28 AM
I just came across these, was wondering how they work? I think they are some sort of synthetic opiate but not sure at all, I don't have numbers/picture, but the guy said they are the generic ones.Ultram (Tramadol) is a kinda like a "quasi-narcotic" analgesic, and is used in the treatment of moderate to severe pain. It is a synthetic analog of codeine, but has a low binding affinity to the mu-opioid receptors.

I took this info below from the wikipedia.org:

Tramadol
Tramadol (INN (http://en.wikipedia.org/wiki/International_Nonproprietary_Name)) (pronounced (http://en.wikipedia.org/wiki/Help:Pronunciation) /ˈtrćmədɒl/) is an atypical opioid (http://en.wikipedia.org/wiki/Opioid) which is a centrally acting analgesic (http://en.wikipedia.org/wiki/Analgesic), used for treating moderate to severe pain (http://en.wikipedia.org/wiki/Pain). It is a synthetic agent, as a 4-phenyl-piperidine analogue of codeine (http://en.wikipedia.org/wiki/Codeine),[1] (http://en.wikipedia.org/wiki/Tramadol#_note-0)[2] (http://en.wikipedia.org/wiki/Tramadol#_note-1) and appears to have actions on the GABAergic (http://en.wikipedia.org/wiki/GABA), noradrenergic (http://en.wikipedia.org/wiki/Noradrenaline) and serotonergic (http://en.wikipedia.org/wiki/Serotonin) systems. Tramadol was developed by the German (http://en.wikipedia.org/wiki/Germany) pharmaceutical company (http://en.wikipedia.org/wiki/Pharmaceutical_company) Grünenthal GmbH (http://en.wikipedia.org/wiki/Gr%C3%BCnenthal) and marketed under the trade name Tramal. Grünenthal has also cross licensed the drug to many other pharmaceutical companies that market it under various names.

Tramadol is usually marketed as the hydrochloride salt (tramadol hydrochloride) and is available in both injectable (http://en.wikipedia.org/wiki/Injection_%28medicine%29) (intravenous (http://en.wikipedia.org/wiki/Intravenous) and/or intramuscular (http://en.wikipedia.org/wiki/Intramuscular)) and oral preparations. It is also available in conjunction with paracetamol (http://en.wikipedia.org/wiki/Paracetamol) (acetaminophen).

Tramadol is approximately 10% as potent as morphine (http://en.wikipedia.org/wiki/Morphine), when given by the IV (http://en.wikipedia.org/wiki/Intravenous)/IM route. Oral doses range from 50–400 mg daily, with up to 600 mg daily when given IV (http://en.wikipedia.org/wiki/Intravenous)/IM. The formulation containing APAP contains 37.5 mg of tramadol and 325 mg of paracetamol (http://en.wikipedia.org/wiki/Paracetamol), intended for oral administration with a common dosing recommendation of one or two tabs every four to six hours.




For more information on Tramadol go to http://en.wikipedia.org/wiki/Tramadol
and
http://erowid.org/pharms/tramadol/tramadol.shtml