MK-801 aka dizocilpine....
Posted March 12 2008 - 01:02 AM
Posted March 12 2008 - 04:59 AM
Seriously. This chemical is so potent and dangerous, longer lasting than PCP and active at LSD-like dosages. Someone will die from it. I have a bad feeling. Why not just use Ketamine, unless you just want to get the chemical to "have it" and not use it. It even says on Wikipedia that it is not very recreational.
This alone scares the shit out of me. If everyone with some money and a few sources has access to this chemical, there will be many, many overdoses, most likely. It's active at 50-100mcg!!!!! How the fuck are you going to dose it? I mean, if you knew what you were doing fully and had a great scale, you could dose (somewhat) correctly. But this stuff is not like LSD, where if you fuck up the dose you'll simply end up tripping hard. If you fuck up the dose, you will probably die. I bet eventually, someone is going to end up fucking up, despite my warnings, and take like a milligram on accident and end up dying or running around the streets naked cutting themselves, then waking up in jail with no recollection of what happened at all. This could ruin the whole RC scene for everyone.
Little is known in this context about its effects, dosage, and risks. Dizocilpine's high potency makes its dosage more difficult to accurately control when compared to other similar drugs. As a result, the chances of overdosing are high. Users tend to report that the experience is not as enjoyable as other dissociative drugs, and it is often accompanied by strong auditory hallucinations. Also, dizocilpine is much longer-lasting than similar dissociative drugs such as ketamine and phencyclidine (PCP), and causes far worse amnesia and residual deficits in thinking, which have hindered its acceptance as a recreational drug
Please, for the sake of your own health and the psychoactive community, don't play with neurotoxic drugs like this, especially when Ketamine has the same effects and is much, much more recreational and shorter lasting and safe.
I mean, it was scrapped during research due to its failure to show safety.
Please, before anyone thinks about ordering/trying this, think about your health and how much it means to you. Also think about all the bad things that could happen while under the influence of it. I don't think it "puts you down" like Ketamine, so I would assume you can walk around like on PCP (this is not good at all) and wreak chaos. Also, please think about the consequences your actions could have on the research chemical community in general. Just IM 100mg of K, would most likely be a lot more fun.
Thus NMDA receptor antagonists including MK-801 have been extensively studied for use in treatment of diseases with excitotoxic components, such as stroke, traumatic brain injury, and neurodegenerative diseases such as Huntington's, Alzheimer's, and amyotrophic lateral sclerosis. MK-801 has shown effectiveness in protecting neurons in cell culture and animal models of excitotoxic neurodegeneration.
However, NMDA antagonists like MK-801 have largely failed to show safety and effectiveness in clinical trials, possibly due to inhibition of NMDA receptor function that is necessary for normal neuronal function.
MK-801 had a promising future as a neuroprotective agent until neurotoxic-like effects, called Olney's Lesions, were seen in certain brain regions of test rats. Merck, a drug company, promptly dropped development of MK-801.
Look at this, they don't even know how long it lasts on Wikipedia. All they say is that it is "much longer lasting" than PCP. That could mean it lasts days, who knows?
Here's a few snippets of two Erowid MK-801 trip reports.
Half life ?
This exercise in “recapitulation” relates to another disassociative experience on MK-801. Because the lack of much needed information on the internet about this disassociative, I overdosed on this drug and suffered long lasting brain damage. I have no business taking a drug that I know nothing about, and this was altogether my fault too. It is not me to put down any drug, and please don’t think that I’m putting down this drug. I’m putting down the lack of information about this drug and my own irresponsibility.
If anyone comes across MK-801, I urgy them to take supersmall doses. The doses are small like acid. Under 1 milligram to a couple milligrams is probably right. However I’ve never accurately weighed my dose(s), which of course is what lead to brain damage.
I took MK801 for 3 or 4 days and ended up tripping for 3 to 4 weeks. I gave one dose to a friend and he tripped for two days. It is an amazingly good drug and the vibrations and body high are so good, & the sex. But it also almost killed me because of my stupidity, or my stupidity almost killed me. After not being able to stop tripping for about one week in, I began pissing and shitting blood, I became retarded. Flashing and strobing couldn’t quit making my field of vision come toward me, to the point that it was actually devouring me.
Pissing and shitting blood....sounds like he had a great trip.
Mk-801 is VERY wicked.. I could only describe this as the 'evil zombie effect' - my body keeps going but the brain isn't there. There are some 'holes' in my memory in the last 24hrs..
Let me add that this was 100% dysphoric. On the other hand, when I've had this type of experience before on other drugs, the voices were all male and accentless. I actually associate the 'radio in the head' bit with LSD and I never considered it anything but a hallucination - when I've had too much and I want it to stop, in my bedroom in the dark, etc.. This, however, seemed VERY MUCH like telepathy. The ketamine telepathy experience is totally different - it's like being in love so much I just think the same things. The mk-801 is like having a television going in the next room without visuals, so the dialogue doesn't make sense.
This last guy seems to LOVE Ketamine, claims to regularly telepathically communicate with his pet rats while on K. I don't think he liked this stuff.
The mk-801 was like a horror novel phone call from hell.. It was MUCH more distinct and powerful than the pseudo-psi effects of K or DXM, but it was also very WRONG. Ever had the phone ringing and you pick it up and there's no one there, but you listen and listen and there's this whispering and then you slam down the phone.? - Well, imagine that was a radio in your room you couldn't turn it off or get away from. That's what it was like.
In any case, I'd like to say that mk-801 is definitely NOT recreational.
There is memory impairment, and significant mental impairment, kinda like valium - it just makes me 'dumb'. For the most part, it seems to be a VERY powerful psi amplifier with almost no recreational value. Also, even the tiniest amount of mk-801 doesn't dissolve very well - there is still visible particulate matter, which might be dust or might be not.. It was dissolved using distilled water, there shouldn't be any impurities, but there are.
I'm done with this compound.. I did try a 200µg sublingual dose, but all I really did was zone out and stare, with a strange heavy feeling in the chest. I'm writing this report under the effect (forgive me for being scatterbrained), but this time I'm aware of the mental impairment and being more careful about typos, at least I hope. I plan on taking ambien to sleep - there is evidence that benzo's reduce the NAN effect.
The whole purpose of this was that I can't really afford ketamine.. With mk-801 (+), maybe 1mg costs the same as 200mg of Ketamine. I had hoped that maybe 500ug would be an experience, but I'm just not going to go there. Geez, my head is still ringing, weird not rightness!
Posted March 12 2008 - 06:13 AM
if you have to ask you're not experienced enough to be dealing with such a chemical.
yeah, i completely agree
even 'regular' rc are extremely dangerous, even if they can have normal 50-100mg dosage... this stuff here, is active at micrograms dose!
this stuff is not recreational... it seems to be like datura ..
Posted March 12 2008 - 07:56 AM
Posted March 12 2008 - 09:52 AM
Posted March 12 2008 - 10:26 AM
I was just reading this thread thinking 'damn, I like disassociatives, but fuck that shit.' Now your comment scared the shit out of me. I hope no one is that dumb & greedy.
Hmmm, this sounds aweful, I hope I never get some blotters with this shit.
Posted March 12 2008 - 01:12 PM
Posted March 15 2008 - 08:13 AM