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how to hydrolize lisdexamfetamine in vyvanse


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#1 justsayno0

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Posted August 12 2007 - 03:08 PM

lisdexamfetamine is made up of L-lysine and d-amphetamine. When takin the bodies amino acids break down and hydrolize the L-lysine from the d-amphetamine, slowly releasing the d-amphetamine so it can become active. My question is, is there a way to hydrolize lisdexamfetamine so you can activate the d-amphetamine before taking it? So you can turn the extended release into instant release and have the euphoric effect of adderall.

#2 framesh1ft

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Posted November 23 2007 - 10:41 PM

my best guess for the time being /// charge the amino group with some acid (i don't know the pK right now) run on a CE column and elute with a gradient of methanol ----> methanol + diethanoloamine base solution.
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