DXM and Opiates
Posted July 28 2007 - 02:42 PM
I read basicallly that the DXM lowers ur tolerance for opiates while the DXM is in ones system.. so basically 40mgs of Oxycodone would feel more like 60mgs while on DXM..(im not sure if those figures are accurate but im just using it as an example).
I also read that White Grapefruit juice will potentiate opiates as well..but im not sure if it works with oxy and hydrocodone.. I've tried it plenty of times but don't really notice much of a difference and if i do its maybe like a 10% increase.. Anyone else have any input on the white grapefruit juice and opiates?
Also anyone with some DXM information and the mixing it with opiates??? (i read you need to take about 60-80mgs of pure DXM b4 dosing)
Posted July 29 2007 - 05:39 AM
Posted August 02 2007 - 10:50 AM
Posted August 03 2007 - 11:55 PM
Posted August 04 2007 - 04:19 PM
Posted September 23 2007 - 09:50 PM
You can use tagamet. Take a dose. wait 45 minutes and take some antacids. After 15 more minutes- it is now an hour and u can take the opiate.
Posted September 24 2007 - 04:59 AM
"DXM seems to enhance the painkilling ability of opiates without adding to the side effects, and in practice the patient can lower the dose of opiates while maintaining analgesic effect (37). As an added bonus, DXM seems to prevent opiate tolerance (see next section). DXM by itself has only marginal analgesic effect if any (373,375)."
So, YMMV, but it looks like taking a little DXM (Not a high dose) can be beneficial to users in multiple ways. While I do not advise doing opiates, and I do advise caution, there may be positives to the whole issue.
"DXM, as well as other dissociatives, seems to prevent and even reverse tolerance to (and thus physical addiction to) many drugs. In the case of opiates, DXM has been used to treat withdrawal symptoms (169). DXM plus diazepam (ValiumTM) was tested and found to be more effective at combating the symptoms of heroin withdrawal (goose flesh, tremors, pupil dilation, joint pains, etc.) than chlorpromazine (ThorazineTM) plus diazepam (34). A further study verified this and found that adding tizanidine (an alpha-2 adrenergic agonist) to the DXM+diazepam cocktail was even more effective (133).
Dissociatives have also been found to reverse or prevent tolerance to cocaine (247), nicotine (249), and alcohol (232), and some researchers have suggested that DXM (and other NMDA antagonists) may be universally useful in most if not all drug addictions."
Be careful though.
"Dissociatives prevent tolerance to opiates (248) and can alleviate opiate withdrawal (254). On the other hand, combining the two may increase the chance for respiratory depression and fatal overdose. "
Posted December 22 2008 - 06:45 PM